Microbiological profile of catheter-related blood stream infections in the internal medicine medical ward at Conjunto Hospitalar do Mandaqui

Abstract

Hospitalar do Mandaqui, the lack of support for outpatient dialysis forces patients to remain hospitalized for extended periods, increasing the risk of these infections. Central venous catheter insertion, common in various clinical contexts, is essential but may require empirical antibiotic therapy when infection is suspected. Understanding the microbiological profile is crucial for effective management. A descriptive study conducted with data from the Hospital Infection Control Commission at Mandaqui analyzed catheter-associated bloodstream infections from January to December 2023. Results indicated a high prevalence of resistant Gram-positive bacteria, such as Staphylococcus aureus and coagulase-negative staphylococci, and multidrug-resistant Gram-negative bacteria, such as Klebsiella pneumoniae and Acinetobacter baumannii. Rare fungal infections were also observed. Resistance to widely used antibiotics, such as beta-lactams and carbapenems, makes treatment challenging, requiring alternatives like glycopeptides and polymyxins. Preventive measures, such as hand hygiene and early catheter removal, combined with constant surveillance and rational use of antimicrobials, are essential to reduce the spread of resistant microorganisms. The microbiological profile obtained guides an initial broad-spectrum empirical therapy, but controlled clinical trials are needed to validate specific therapeutic regimens.