The Oral Microbiome And Periodontal Disease: Biofilm, Dysbiosis And The Immune System
DOI:
https://doi.org/10.5281/zenodo.12789386Keywords:
Biofilm, Dysbiosis, Microbiota, PeriodonticsAbstract
The human microbiome is defined as the entire genomic content of the microorganisms inhabiting a particular human body site. Emerging evidence suggests the importance of having a balanced microbiota to maintain proper immune response to provide health to the full body and the oral tissues and stomatognathic functions. Periodontitis (PD) is a chronic inflammatory disease affecting the teeth's supporting tissues. The etiology is multifactorial and subgingival dental biofilm stimulates an inflammatory and immune response. The association between the oral microbiome and PD is critical, as the disease is mainly triggered by an imbalance in the oral microbial community, known as dysbiosis. The article intends to describe the imbalance in the oral microbiota that leads to the development of periodontitis. To sustain an integrative literature review 53 articles published in English were analyzed. The oral microbiome influences the process and outcome of periodontal disease. The alteration in the composition of oral microflora is an indicator of the initiation of diverse diseases.
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